Death by asexuality: IU biologists uncover new path for mutations to arise
"Contagious Asexuality" is Dominant in Sexual Genotypes
Univ. of Indiana media release
Ground-breaking new research from a team of evolutionary biologists at Indiana University shows for the first time how asexual lineages of a species are doomed not necessarily from a long, slow accumulation of new mutations, but rather from fast-paced gene conversion processes that simply unmask pre-existing deleterious recessive mutations.
Geneticists have long bet on the success of sexual reproduction over asexual reproduction based in a large part on the process known as Muller’s ratchet, the mechanism by which a genome accrues deleterious and irreversible mutations after the host organism has lost its ability to carry out the important gene-shuffling job of recombination.
The new work from the laboratory of IU Distinguished Professor of Biology Michael Lynch instead indicates that most deleterious DNA sequences contributing to the extinction process are actually present in the sexual ancestors, albeit in recessive form, and simply become exposed via fast-paced gene conversion and deletion processes that eliminate the fit genes from one of the parental chromosomes.
After sequencing the entire genomes of 11 sexual and 11 asexual genotypes of Daphnia pulex, a model organism for the study of reproduction that is more commonly known as the water flea, the team discovered that every asexual genotype shared common combinations of alleles for two different chromosomes transmitted by asexual males without recombination…
(read more: University of Indiana)

Death by asexuality: IU biologists uncover new path for mutations to arise

"Contagious Asexuality" is Dominant in Sexual Genotypes

Univ. of Indiana media release

Ground-breaking new research from a team of evolutionary biologists at Indiana University shows for the first time how asexual lineages of a species are doomed not necessarily from a long, slow accumulation of new mutations, but rather from fast-paced gene conversion processes that simply unmask pre-existing deleterious recessive mutations.

Geneticists have long bet on the success of sexual reproduction over asexual reproduction based in a large part on the process known as Muller’s ratchet, the mechanism by which a genome accrues deleterious and irreversible mutations after the host organism has lost its ability to carry out the important gene-shuffling job of recombination.

The new work from the laboratory of IU Distinguished Professor of Biology Michael Lynch instead indicates that most deleterious DNA sequences contributing to the extinction process are actually present in the sexual ancestors, albeit in recessive form, and simply become exposed via fast-paced gene conversion and deletion processes that eliminate the fit genes from one of the parental chromosomes.

After sequencing the entire genomes of 11 sexual and 11 asexual genotypes of Daphnia pulex, a model organism for the study of reproduction that is more commonly known as the water flea, the team discovered that every asexual genotype shared common combinations of alleles for two different chromosomes transmitted by asexual males without recombination…

(read more: University of Indiana)

  1. suchcuriousthings reblogged this from rhamphotheca
  2. ocean-depths reblogged this from griseus
  3. phillionaire reblogged this from rhamphotheca
  4. whoi-really-am reblogged this from rhamphotheca
  5. i-need-a-time-machine reblogged this from rhamphotheca
  6. scienceismyopium reblogged this from ifveniceissinking
  7. michimera reblogged this from smartpeopleposting
  8. blue-chameleonn reblogged this from octopamine
  9. octopamine reblogged this from sagansense
  10. retromantique reblogged this from sagansense
  11. c-f-a-f reblogged this from rhamphotheca
  12. ifveniceissinking reblogged this from sagansense
  13. fivekage reblogged this from sagansense
  14. sovietproblems reblogged this from sagansense
  15. quoi-le-quark reblogged this from science-sexual
  16. science-sexual reblogged this from letmebeme9514 and added:
    I think it’s funny how in one day my bio 2 class taught me more about evolutionary biolgy than my evolutionary biology...
  17. suck-it-blured reblogged this from rifkind-moonchild
  18. rifkind-moonchild reblogged this from sagansense
  19. frankenopolis reblogged this from adionysian
  20. adionysian reblogged this from deadrevolutionaries
  21. thorninsky reblogged this from sagansense
  22. diegoa5 reblogged this from sagansense
  23. hardtobeoriginal reblogged this from manicfix
  24. manicfix reblogged this from escapist-fiction
  25. 8312092 reblogged this from sagansense and added:
    Summary: They’ve identified genes that transmit through sexual reproduction that cause asexuality in females, and cause...
  26. arangbruh reblogged this from sagansense
  27. deadrevolutionaries reblogged this from laikas-owner